Abstract: Root-knot nematode disease is a common and important disease in facility vegetable cultivation, which seriously affects crop yield and quality. This paper reviewed the research progress of root-knot nematode disease control from the aspects of agricultural control, physical control, chemical control and biological control. Through the study and comparison of the advantages and disadvantages of various control methods and application effects, it was pointed out that the comprehensive control technology was an effective measure to reduce the use of pesticides and improve the soil microecology. It was an effective measure of economy, efficiency, green and environmental protection, in order to provide reference for the control of vegetable root-knot nematode disease.